Endocrine Abstracts

The mechanism of the adverse influence of genistein; a soya phytoestrogen on foetal development is still poorly understood. Previous reports showed adverse effects on thyroid and leptin hormone, C-reactive protein and thyroxin kinase activities. This study evaluated the changes to the level of the insulin-like growth factor-I (IGF-1) and placenta growth factor (PGF) in rat pregnancy exposed to genistein. Pregnant rats grouped into 2 mg/kg and 4 mg/kg genistein treated groups w...